Lloyd Gregory_Profile_Photo.jpgIn this last week, I have been involved in several interactions and situations that have prompted me to write this short piece about the power of perspectives.  In follow-up conversations, it has become clear just how important it is to see things from all sides and by doing so, we reach greater understanding and acceptance.

In the world of translational and clinical research, precision is everything. A well-crafted protocol is the backbone of any study; it outlines the objectives, methodology, ethical considerations, and data analysis plans. Yet even the most meticulously written protocol can be misunderstood, leading to confusion, delays, or even flawed execution.

Why Perspective Matters

Every researcher, reviewer, or collaborator brings their own lens to a protocol. These lenses are shaped by discipline, experience, cultural background, and even personal biases and are all valid. A statistician might zero in on sample size calculations, while a clinician might focus on patient safety. A social scientist may interpret participant engagement differently than a biomedical researcher. These varied perspectives are not just inevitable, they're invaluable.

However, when these are not acknowledged, misinterpretation and frustration can arise. What one person sees as a clear instruction, another might view as ambiguous or even contradictory. When initiating translational and clinical research is seen as the one unifying objective we can all get behind, avoiding delays due to misunderstanding or miscommunication is where we all have a role to play.

Common Pitfalls of a Single-Perspective Approach

  1. Assumed Knowledge: Authors may assume readers understand certain terminology or rationale, leading to gaps in comprehension.
  2. Over-Specification or Under-Specification: Details that seem excessive to one reader may be essential to another.
  3. Misaligned Expectations: Different stakeholders (e.g., ethics committees, R&D Departments, funders and collaborators) may interpret the same protocol differently based on their priorities.

Bridging the Gap: Embracing Multiple Perspectives

To avoid these pitfalls, it's crucial to actively seek out and integrate diverse viewpoints during the protocol development and review process. Here are some thoughts to help bring clarity and greater understanding:

  • Collaborative Drafting: Involve multidisciplinary team members early in the writing process. Their input can highlight blind spots and improve clarity.
  • Peer Review with Purpose: Encourage reviewers to comment not just on content, but on clarity and assumptions. Ask: “What part of this protocol might be misunderstood?”
  • Plain Language Summaries: Including a lay summary can help ensure that the protocol is understandable beyond the core research team.
  • Feedback Loops: Pilot the protocol with a small group and gather feedback on interpretation. This can reveal surprising ambiguities.

The Emotional Side of Misinterpretation

Misunderstandings don’t just slow down research, they can also cause frustration, erode trust, and damage team morale. When someone feels their perspective is dismissed or misunderstood, collaboration suffers. Recognising and validating different viewpoints fosters a culture of respect and shared ownership.

Conclusion: Perspective elevates understanding, quality and research integrity

Understanding a research protocol isn’t just about reading comprehension; it’s about empathy, communication, and collaboration. By embracing the power of perspectives, we not only reduce misinterpretation and frustration but also elevate greater understanding, quality and integrity of our research.